Search results for "therapy [Ciliopathies]"
showing 10 items of 2852 documents
Effects of Sparring Load on Reaction Speed and Punch Force During the Precompetition and Competition Periods in Boxing.
2017
Seven, male, national-level boxers (age, 20.3 ± 2.7 years; height, 1.80 ± 0.06 m; mass, 73.8 ± 11.1 kg) participated in this study to investigate the effects of sparring on reaction time and punch force of straight punches measured during the precompetition and competition periods. Heart rate and blood lactate concentrations were also monitored. Sparring load was chosen in accordance with the current rules: 3 × 3-minute bouts with 1-minute break in between. Reaction time of rear straight lengthened (p < 0.01) during the sparring load of the precompetition period after the third round (to 390 milliseconds) in comparison to the competition period (to 310 milliseconds). Reaction time of lead s…
Age-Related Differences in 100-m Sprint Performance in Male and Female Master Runners
2003
This study was undertaken to investigate age-related differences in the velocity and selected stride parameters in male and female master sprinters and to determine which stride characteristics were related to the overall decline in the performance of the 100 m with age.The performances of 70 finalists (males 40-88 yr, females 35-87 yr) at the European Veterans Athletics Championships were recorded using two high-speed cameras (200 Hz) with a panning video technique and distance markers at 10-m intervals. Velocity, stride length (SL), stride rate (SR), ground contact time (CT), and flight time (FT) during the acceleration, peak velocity, and deceleration phases of the 100-m race were determ…
Bone Density, Structure and Strength, and Their Determinants in Aging Sprint Athletes
2012
This study was undertaken to examine bone properties in masters sprinters of different ages and younger reference subjects. In addition, the association of sport-specific ground reaction force, muscle, training, and hormone characteristics with the bone parameters was evaluated in the athletes.Bone densitometric, structural, and strength parameters were assessed by peripheral quantitative computed tomography at the distal and midtibia in 83 male sprinters (40-85 yr) and 19 physically active referents (31-45 yr). Between-group differences were analyzed by ANCOVA with body mass and height as covariates.Bone values were generally greater in athletes than referents, the greatest differences bei…
Acute Hormonal Responses to Heavy Resistance Exercise in Men and Women at Different Ages
1995
To examine acute endogenous hormonal responses to heavy resistance exercise eight young women (YW) and eight young men (YM) in the 30-year age group, seven middle-aged women (MW) and eight middle-aged men (MM) in the 50-year age group as well as eight elderly women (EW) and eight elderly men (EM) in the 70-year age group performed a heavy resistance exercise session with three different exercises (bench press, sit-up exercise and bilateral leg press). The relative loading intensity and volume of the exercise session were kept the same for each subject so that they performed each of the 5 sets of each exercise with the maximal load possible for 10 repetitions per set (10 repetition maximum).…
STRENGTH AND POWER PROFILES OF THE LOWER AND UPPER EXTREMITIES IN MASTER THROWERS AT DIFFERENT AGES
2007
Ojanen, T., T. Rauhala, and K. Hakkinen. Strength and power profiles of the lower and upper extremities in master throwers at different ages. J. Strength Cond. Res. 21(1):216-222. 2007.-Thirty-two master athletes (shot put, discus, and hammer throw) were divided into 4 groups according to their age (T40 [40 years of age], 50 [50 years of age], 60 [60 years of age], and 75 [75 years of age]). Twenty-eight age-matched men served as controls (C40 [40 years of age], 50 [50 years of age], 60 [60 years of age], and 75 [75 years of age]). The subjects were tested for maximal isometric strength of the lower and upper extremities. Power was measured by performing jump squats and bench press in the S…
Technical determinants of biathlon standing shooting performance before and after race simulation
2018
The aim of this study was to identify performance- determining factors in biathlon standing shooting in rest and after intense exercise. Eight Finnish national- and nine junior- team biathletes participated in the study. Participants fired 40 resting shots (REST) and 2 × 5 competition simulation shots (LOAD) after 5 minutes of roller skiing at 95% of peak heart rate. Hit percentage, aiming point trajectory and postural balance were measured from each shot. Cleanness of triggering (ATV, movement of the aiming point 0- 0.2 second before the shot) and vertical stability of hold (DevY) were the most important components affecting shooting performance both in REST (DevY, R = −0.61, P < .01; ATV,…
Anaerobic performance testing of professional soccer players 1995-2010
2013
Purpose:To compare sprint and countermovement-jump (CMJ) performance among competitive soccer players as a function of performance level, field position, and age. In addition, the authors wanted to quantify the evolution of these physical characteristics among professional players over a 15-y period.Methods:939 athletes (22.1 ± 4.3 y), including national-team players, tested 40-m sprint with electronic timing and CMJ on a force platform at the Norwegian Olympic Training Center between 1995 and 2010.Results:National-team and 1st-division players were faster (P < .05) than 2nd-division (1.0–1.4%), 3rd- to 5th-division (3.0–3.8%), junior national-team (1.7–2.2%), and junior players (2.8–3.7…
Biweekly oxaliplatin combined with oral capecitabine (OXXEL regimen) as first-line treatment of metastatic colorectal cancer patients: a Southern Ita…
2005
Oxaliplatin 100 mg/m(2) iv on day 1, and capecitabine 1,000 mg/m(2) orally bid from day 1 (evening) to day 11 (morning) were administered every 2 weeks (OXXEL regimen) to 38 patients as first-line treatment for metastatic colorectal carcinoma. A total of 318 cycles were administered, with a median of 8 (range, 4-12) cycles per patient. Response rate (RR) was 45% (95% confidence interval (CI), 29%-62%), with 7 complete responses and 10 partial responses; furthermore, 12 patients showed a stable disease, so that a disease control was achieved in 29 (76%) patients. RR was greater among patients with performance status 0 (52%), without weight loss (52%), younger than 65 years (50%), and previou…
Gemcitabine (GEM) plus oxaliplatin, folinic acid, and 5-fluorouracil (FOLFOX-4) in patients with advanced gastric cancer
2005
Abstract BACKGROUND AND AIMS: oxaliplatin in combination with folinic acid (FA) and infusional 5-fluorouracil (5-FU) has shown significant anti-tumor activity in gastric cancer patients (FOLFOX). Previous studies have shown that gemcitabine (GEM), a new fluorinated anti-metabolite, enhances the individual anti-tumor activity of either 5-FU or oxaliplatin. We have therefore designed a multi-center phase II trial in order to test a novel GEM+FOLFOX-4 regimen in patients with metastatic gastric cancer. METHODS: we enrolled 36 patients, 28 males and 8 females, with an average age of 64.4 years (range 37-78), who received bi-weekly treatment with GEM (1,000 mg/m2 on day 1), levo-FA (100 mg/m2 on…
Accident ahead? Difficulties of drivers with and without reading impairment recognising words and pictograms in variable message signs
2017
A timely and accurate acquisition of the information provided by variable message signs (VMS) can be crucial while driving. In the current study, we assess the difficulties of adults with dyslexia acquiring the information shown in VMS and provide evidence to discuss the controversial use of pictograms as potential countermeasures. Twenty-two adults with dyslexia and 22 matched controls completed a simulated driving session. The legibility of 12 VMS was assessed, including six text messages (e.g. "ACCIDENT") and six single pictograms (e.g. the icon for "accident ahead"). On average, participants with dyslexia started reading text messages when they were closer to the VMS. In addition, while…